發表評論-心理與性-萬維博客-萬維讀者網（電腦版）

【摘要】數字健康干預 (DHI) 在治療心理健康障礙方面展現出良好的前景。然而，現有的薈萃分析研究方法論上存在差異，研究對象涵蓋臨床、非臨床和跨診斷人群，這阻礙了對DHI有效性的全面理解。因此，我們對隨機對照試驗的薈萃分析進行了一項總體綜述，旨在研究DHI對特定的心理障礙的有效性並評估證據質量。我們檢索了三個公共電子數據庫，檢索時間為建庫至2024年2月，共納入16項研究。與積極干預措施相比，DHI 對精神分裂症譜系障礙、重度抑鬱障礙、社交焦慮障礙和驚恐障礙均有效。此外，與等待治療相比，DHI對特定恐懼障礙、廣泛性焦慮障礙、強迫障礙、創傷後應激障礙和神經性貪食症也具有顯著的治療效果。除廣泛性焦慮障礙相關結局指標評級為中等外，大多數情況下證據質量被評為極低或低。為了將DHI納入臨床實踐，需要進一步開展高質量研究，明確目標人群，並採用可靠的對照方法。

[Summary] Digital health interventions (DHIs) show promise for the treatment of mental health disorders. However, existing meta-analytical research is methodologically heterogeneous, with studies including a mix of clinical, non-clinical, and transdiagnostic populations, hindering a comprehensive understanding of DHI effectiveness. Thus, we conducted an umbrella review of meta-analyses of randomised controlled trials investigating the effectiveness of DHIs for specific mental health disorders and evaluating the quality of evidence. We searched three public electronic databases from inception to February, 2024 and included 16 studies. DHIs were effective compared with active interventions for schizophrenia spectrum disorders, major depressive disorder, social anxiety disorder, and panic disorder. Notable treatment effects compared with a waiting list were also observed for specific phobias, generalised anxiety disorder, obsessive-compulsive disorder, post-traumatic stress disorder, and bulimia nervosa. Certainty of evidence was rated as very low or low in most cases, except for generalised anxiety disorder-related outcomes, which showed a moderate rating. To integrate DHIs into clinical practice, further high-quality studies with clearly defined target populations and robust comparators are needed.

論文原文：Cristina Crocamo, Dario Palpella, Daniele Cavaleri, Christian Nasti, Susanna Piacenti, Pietro Morello, et al. (2025). Digital health interventions for mental health disorders: an umbrella review of meta-analyses of randomised controlled trials. The Lancet / Digital Health, Volume 7, Issue 8, August 2025.

https://doi.org/10.1016/j.landig.2025.100878

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