物理治療對男性早泄的療效：一項系統綜述與薈萃分析

Effectiveness of physiotherapy in male premature ejaculation. A systematic review and metaanalysis

——《性醫學雜誌》第23卷第5期，2026年5月——

<The Journal of Sexual Medicine>, Volume 23, Issue 5, May 2026

【摘要】引言：臨床上將早泄（PE）定義為陰道內射精潛伏期（IELT）為1分鐘或更短。儘管藥物治療已顯示出快速且有效的療效，但常伴隨不良副作用。相比之下，物理治療方法提供了一種更安全的替代方案，其產生不良反應的風險較低。目的：旨在評估物理治療干預措施在延長被診斷為早泄的男性患者IELT方面的療效，並將其與藥物治療進行比較。方法：研究人員對多個數據庫（PubMed、PEDro、Scopus和Researchgate）進行了系統檢索，以識別過去10年內發表的臨床試驗。符合納入標準的研究包括那些在早泄男性患者中，以IELT作為主要結局指標，並將物理治療與藥物干預進行比較的研究。研究質量評估採用PEDro量表進行。隨後對數據進行匯總，並完成了Meta分析。本系統綜述依據《系統綜述和Meta分析優先報告條目》（PRISMA）指南聲明進行。該綜述已在PROSPERO數據庫註冊，註冊號為CRD42024613802（對審稿人實行盲法）。結果：共有6項研究符合納入標準並被納入分析，涵蓋了總計416名參與者。匯總效應具有統計學意義（P = 0.03），顯示IELT的平均差異為-0.80秒（95%置信區間：-1.53至-0.06），結果顯著傾向於達泊西汀組；各研究之間存在高度異質性（I² = 83%）。結論：Meta分析結果表明，對於患有終生性早泄的男性而言，30 mg劑量的達泊西汀在延長IELT方面顯著優於物理治療。物理治療可被視為一種安全且有益的干預手段，對於無法耐受藥物治療的患者而言，它是一種極具潛力的替代療法。儘管如此，定性綜述結果提示，採用綜合治療方案能在延長IELT方面取得最為顯著的改善效果。

【關鍵詞】早泄，物理治療手段，藥物治療

[Abstract] Introduction: Premature ejaculation (PE) is clinically defined as an intravaginal ejaculatory latency time (IELT) of 1 min or less. While pharmacological treatments have demonstrated rapid and effective results, they are frequently associated with adverse side effects. In contrast, physiotherapeutic approaches offer a safer alternative, with a lower risk of undesirable reactions. Objectives: To assess the efficacy of physiotherapeutic interventions in increasing IELT, compared to pharmacological treatment, in men diagnosed with PE. Methods: A systematic search was conducted across multiple databases (PubMed, PEDro, Scopus, and Researchgate) to identify clinical trials published within the past 10 years. Eligible studies included those that compared physiotherapy with pharmacological interventions, using IELT as the primary outcome variable in male patients with PE. A quality assessment was performed using the PEDro scale. The data were pooled and a meta-analysis was completed. This systematic review was conducted in accordance with the (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) PRISMA guideline statement. It was registered in the PROSPERO database with registration number CRD42024613802 (blinded for reviewers). Results: Six studies, encompassing a total of 416 participants, met the inclusion criteria and were analyzed. The pooled effect is statistically significant (P = .03), showing a mean difference in IELT of −0.80 s (95% confidence interval, −1.53 to −0.06) which significantly favors dapoxetine, with a high heterogeneity between studies (I2 = 83%). Conclusion: The results of the meta-analyses suggest that dapoxetine at a dose of 30 mg is significantly more effective than physiotherapy for prolonging IELT in men with lifelong PE. Physiotherapy can be considered a safe and beneficial intervention, positioning it as a promising alternative for patients who are intolerant to pharmacological treatment. Nevertheless, the qualitative review suggests that a combined therapeutic approach yields the most significant improvements in IELT.

[Key words] premature ejaculation, physical therapy modalities, drug therapy

論文原文：Esther M Medrano-Sánchez, Ana López-del-Castillo, Maud Boisseau, et al. (2026). Effectiveness of physiotherapy in male premature ejaculation. A systematic review and metaanalysis. The Journal of Sexual Medicine, Volume 23, Issue 5, May 2026.

https://doi.org/10.1093/jsxmed/qdag096

（翻譯兼責任編輯：MARY）

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