想必大家知道萬維是在加拿大運營的一家網站，但你要不是Pascal博座的粉兒，就可能不知道“苗駕”（vaxxed driving）這回事，更不太可能知道有那麽一群加拿大科學家終於對他忍無可忍而對unvaxxed driving做了非常及時、非常科學的研究，光是被研究的個體就多達11,270,763個。此石破天驚的研究論文已經發表在大名鼎鼎的The American Journal of Medicine，全文可在 https://www.amjmed.com/article/S0002-9343(22)00822-1/fulltext 免費拜讀，也可以免費下載自行裱起來當作聖誕禮物饋贈開車的親友。

    （背景突然有加拿大國歌響起，O Canada ...，建議鍵盤前各位請默唱3遍，對這群可愛的科學家表示由衷的敬意）

    爲方便起見，我把該論文的摘要黏貼在下面兩條分割綫之間。我本人不是數據科學家，也為了避免引起帶風向的嫌疑，我就不在帖子正文中評論了，但會爭取在周末有空時在評論區“知無不言言無不盡”。

Background

Coronavirus disease (COVID) vaccine hesitancy is a reflection of psychology that might also contribute to traffic safety. We tested whether COVID vaccination was associated with the risks of a traffic crash.

Methods

We conducted a population-based longitudinal cohort analysis of adults and determined COVID vaccination status through linkages to individual electronic medical records. Traffic crashes requiring emergency medical care were subsequently identified by multicenter outcome ascertainment of all hospitals in the region over a 1-month follow-up interval (178 separate centers).

Results

A total of 11,270,763 individuals were included, of whom 16% had not received a COVID vaccine and 84% had received a COVID vaccine. The cohort accounted for 6682 traffic crashes during follow-up. Unvaccinated individuals accounted for 1682 traffic crashes (25%), equal to a 72% increased relative risk compared with those vaccinated (95% confidence interval, 63-82; P < 0.001). The increased traffic risks among unvaccinated individuals extended to diverse subgroups, was similar to the relative risk associated with sleep apnea, and was equal to a 48% increase after adjustment for age, sex, home location, socioeconomic status, and medical diagnoses (95% confidence interval, 40-57; P < 0.001). The increased risks extended across the spectrum of crash severity, appeared similar for Pfizer, Moderna, or other vaccines, and were validated in supplementary analyses of crossover cases, propensity scores, and additional controls.

Conclusions

These data suggest that COVID vaccine hesitancy is associated with significant increased risks of a traffic crash. An awareness of these risks might help to encourage more COVID vaccination.

    Dr. Fauci，你怎麽看？

（欲言又止，但正文真的在此完結了）