针对心理健康障碍的数字健康干预措施：随机对照试验荟萃分析的总体综述 Digital Health Interventions for Mental Health Disorders: An Umbrella Review of Meta-Analyses of Randomised Controlled Trials ——《柳叶刀/数字健康》第7卷第8期，2025年8月—— <The Lancet / Digital Health> Volume 7, Issue 8, Aug. 2025 【摘要】数字健康干预 (DHI) 在治疗心理健康障碍方面展现出良好的前景。然而，现有的荟萃分析研究方法论上存在差异，研究对象涵盖临床、非临床和跨诊断人群，这阻碍了对DHI有效性的全面理解。因此，我们对随机对照试验的荟萃分析进行了一项总体综述，旨在研究DHI对特定的心理障碍的有效性并评估证据质量。我们检索了三个公共电子数据库，检索时间为建库至2024年2月，共纳入16项研究。与积极干预措施相比，DHI 对精神分裂症谱系障碍、重度抑郁障碍、社交焦虑障碍和惊恐障碍均有效。此外，与等待治疗相比，DHI对特定恐惧障碍、广泛性焦虑障碍、强迫障碍、创伤后应激障碍和神经性贪食症也具有显著的治疗效果。除广泛性焦虑障碍相关结局指标评级为中等外，大多数情况下证据质量被评为极低或低。为了将DHI纳入临床实践，需要进一步开展高质量研究，明确目标人群，并采用可靠的对照方法。 [Summary] Digital health interventions (DHIs) show promise for the treatment of mental health disorders. However, existing meta-analytical research is methodologically heterogeneous, with studies including a mix of clinical, non-clinical, and transdiagnostic populations, hindering a comprehensive understanding of DHI effectiveness. Thus, we conducted an umbrella review of meta-analyses of randomised controlled trials investigating the effectiveness of DHIs for specific mental health disorders and evaluating the quality of evidence. We searched three public electronic databases from inception to February, 2024 and included 16 studies. DHIs were effective compared with active interventions for schizophrenia spectrum disorders, major depressive disorder, social anxiety disorder, and panic disorder. Notable treatment effects compared with a waiting list were also observed for specific phobias, generalised anxiety disorder, obsessive-compulsive disorder, post-traumatic stress disorder, and bulimia nervosa. Certainty of evidence was rated as very low or low in most cases, except for generalised anxiety disorder-related outcomes, which showed a moderate rating. To integrate DHIs into clinical practice, further high-quality studies with clearly defined target populations and robust comparators are needed. 论文原文：Cristina Crocamo, Dario Palpella, Daniele Cavaleri, Christian Nasti, Susanna Piacenti, Pietro Morello, et al. (2025). Digital health interventions for mental health disorders: an umbrella review of meta-analyses of randomised controlled trials. The Lancet / Digital Health, Volume 7, Issue 8, August 2025. https://doi.org/10.1016/j.landig.2025.100878 （需要英文原文的朋友，请联系微信：millerdeng95或iacmsp）
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