睡眠质量与时间生物型对主诉勃起障碍的年轻成人自评勃起功能的影响：一项前瞻性观察研究

Impact of sleep quality and chronotype on self-reported erectile function in young adults presenting with erectile complaints: a prospective observational study

——《国际阳痿研究杂志》第38卷第1期，2026年——

<International Journal of Impotence Research> Volume 38, Issue 1, 2026

【摘要】勃起功能障碍（ED）在年轻人群中普遍存在，多种因素可能影响其性功能及生活质量。本研究旨在探讨睡眠质量和时间生物学类型（chronotype）对自述存在勃起困难的年轻男性勃起功能的影响。在这项前瞻性研究中，共纳入了249名患有ED的男性受试者，评估时间跨度为2023年1月至2024年7月。研究收集了所有参与者的社会人口学及临床数据，包括年龄、体重指数（BMI）、合并疾病情况以及激素相关指标。所有受试者均完成了以下问卷调查：《国际勃起功能指数》（IIEF-5）、《匹兹堡睡眠质量指数》（PSQI）、《晨型-夜型问卷》（MEQ）、《抑郁-焦虑-应激量表》（DASS-42）以及《一般健康问卷》（GHQ-28）。研究采用Spearman相关分析和Kruskal-Wallis检验等统计学方法，评估了睡眠质量、时间生物学类型与ED之间的相互关系。受试者的平均年龄为31.03 ± 8.06岁。结果显示存在显著的相关性：睡眠质量较差与勃起功能较弱呈负相关（r=-0.379, p<0.001），而属于“晨型人”（即早睡早起型）的时间生物学类型则与较好的勃起功能呈正相关（r=0.424, p<0.001）。回归分析进一步证实，上述两项因素均是ED的显著预测因子（R²=0.200, p<0.001）。研究提示，睡眠质量和时间生物学类型是ED管理中的关键因素，针对这些因素采取靶向干预措施有望带来积极的治疗成效。

[Abstract] Erectile complaints are prevalent among young adults, with various factors potentially affecting sexual function and quality of life. This study investigates the impact of sleep quality and chronotype on erectile function in young adults who present with self-reported erectile difficulties. In this prospective study, 249 men with ED were included, assessed from January 2023 to July 2024. Sociodemographic and clinical data were collected for all participants, including age, body mass index (BMI), comorbid diseases, and hormonal parameters. All patients completed the following questionnaires: International Index of Erectile Function (IIEF-5), Pittsburgh Sleep Quality Index (PSQI), Morningness-Eveningness Questionnaire (MEQ), Depression Anxiety Stress Scales-42 (DASS-42), and General Health Questionnaire-28 (GHQ-28). Statistical analyses, including Spearman’s correlation and Kruskal-Wallis tests, evaluated the relationships between sleep quality, chronotype, and ED. The average age was 31.03 ± 8.06 years. Significant correlations were found: Poor sleep quality was linked to lower erectile function (r = −0.379, p < 0.001), while morning chronotype correlated with better erectile function (r = 0.424, p < 0.001). Regression analysis confirmed these as significant predictors of ED (R2 = 0.200, p < 0.001). Sleep quality and chronotype are crucial factors in ED management, suggesting targeted interventions could be beneficial.

论文原文: Ali Nebioğlu, Mert Başaranoğlu & Selahittin Çayan (2026).  Impact of sleep quality and chronotype on self-reported erectile function in young adults presenting with erectile complaints: a prospective observational study. International Journal of Impotence Research, Volume 38, Issue 1, Pages 44–50. 2026.

https://doi.org/10.1038/s41443-025-01089-4

（翻译兼责任编辑：MARY）

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