情緒調節作為老年人壓力與炎症之間關聯的保護因素 Emotion regulation as a protective factor in the association between stress and inflammation in older adults ——《健康心理學》第44卷第12期，2025年12月—— <Health Psychology> Volume 44, Issue 12, December 2025 【摘要】情緒調節多樣性和整體情緒調節能力顯著調節了壓力與白細胞介素-6之間的前瞻性關聯。目的：識別在壓力和衰老背景下促進健康的社會心理因素至關重要。情緒調節（ER）可能就是這樣一種保護因素。本研究檢驗了三種形式的情緒調節——個體情緒調節策略的使用、情緒調節策略的多樣性以及整體情緒調節能力——作為感知壓力與老年人炎症之間前瞻性關聯的調節因素。方法：162名60歲以上的成年人完成了基線測量，包括感知壓力、單獨測試的情緒調節策略（情境選擇、情境修正、認知重評和情緒接受），並將這些策略組合成情緒調節多樣性指標，以及整體情緒調節能力的測量。在基線和隨訪（平均6.8個月後）時評估了炎症標誌物（C反應蛋白、白細胞介素-6和腫瘤壞死因子-α）。殘差變化模型檢驗了情緒調節措施作為壓力與炎症之間關聯的調節因素，並調整了基線炎症、人口統計學和健康協變量。分析對每種情緒調節形式的多重炎癥結果進行了校正。結果：沒有一種情緒調節策略能夠調節壓力與炎症之間的前瞻性關聯（p>0.48）。情緒調節多樣性和整體情緒調節能力分別顯著調節了壓力與白細胞介素-6（B=-0.13，調整後p=0.047）和C反應蛋白（B=0.14，調整後p=0.019）之間的前瞻性關聯。較高的情緒調節多樣性和較低的整體情緒調節能力缺陷具有保護作用，並減弱了壓力與炎症之間的關聯。結論：經歷較高壓力的老年人如果採用多種情緒調節策略並具有較高的整體情緒調節能力，則其白細胞介素-6和C反應蛋白水平較低，但其他標誌物水平沒有顯著差異。初步結果表明，除個體策略之外的其他情緒調節方法可能在壓力背景下促進健康的免疫衰老。 【關鍵詞】心理神經免疫學，衰老，情感免疫學，情緒調節多樣性 [Abstract] ER diversity and global ER ability significantly moderated the prospective association between stress and interleukin-6. Objective: Identifying psychosocial factors that promote health in the context of stress and aging is needed. Emotion regulation (ER) may be one such protective factor. The current study tested three forms of ER—use of individual ER strategies, diversity of ER strategies, and global ER ability—as moderators of the prospective association between perceived stress and inflammation in older adults. Method: Adults (N = 162) aged 60+ completed baseline measures of perceived stress, ER strategies (situation selection, situation modification, reappraisal, and emotional acceptance) tested individually, and combined into an ER diversity metric, and a measure of global ER ability. Inflammatory markers (C-reactive protein, interleukin-6, and tumor necrosis factor-α) were assessed at baseline and follow-up (average 6.8 months later). Residualized change models tested ER measures as moderators of the association between stress and inflammation, adjusting for baseline inflammation and demographic and health covariates. Analyses were corrected for testing multiple inflammatory outcomes per form of ER. Results: No one ER strategy moderated the prospective association between stress and inflammation (ps>.48). ER diversity and global ER ability significantly moderated the prospective association between stress and interleukin-6 (B=−.13, padjusted= .047) and C-reactive protein (B= .14, padjusted= .019), respectively. Higher ER diversity and lower deficit in global ER ability were protective and attenuated stress–inflammation associations. Conclusions: Older adults experiencing higher stress who employ a diversity of ER strategies and have higher global ER ability had lower levels of interleukin-6 and C-reactive protein, respectively, but not of other markers. Initial results suggest ER approaches other than individual strategies may promote healthy immune aging in the context of stress. [Key words] psychoneuroimmunology, aging, affective immunology, emotion regulation diversity 論文原文：Rebecca G. Reed (2025). Emotion regulation as a protective factor in the association between stress and inflammation in older adults. Health Psychology, Volume 44, Issue 12, Pages 1105–1115. December 2025. https://doi.org/10.1037/hea0001530 （需要英文原文的朋友，請聯繫微信：millerdeng95或iacmsp）
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