好奇你为何在万恶的资本主义美国受苦,不去金太阳的朝鲜共产主义天堂享福?莫非你已经堕落成资本家的一员了? ---------------------------------------------------------------------------- If you disagree with lesson, just debate please. It is so rude,ill-mannered and impolite for you to ask lesson such ridiculous and mean questions which are irrelevant to the subject.
Thanks a lot for your great suggestions. My boss is quite established in our field. However, He was told recently two of his recent publications won’t count in our university as the IP is not high enough. The reason for IP is not high enough is nothing to do with the quality of these two papers, is because the journal IP in our field is quite lot. Mol micro and JBC are consider to be good, EMBO and Plos pathogen are very good, PNAS is brilliant and you have to be extremely lucky to get into nature or science in our field. Sometimes I don’t understand how people can publish in Nature or Sciences constantly every year. My boss will soon move to another university as he can’t take the pressure anymore here. My boss really wants me to move with him. He is happy I am to be joint first authors in two potential very good papers, which are the other two PhD students work. I have been involved in supervisor all his PhD students.
The reason I chose vaccine field a couple of year ago is because I was targeting vaccine industry and of course I like infection biology and immunology. However, UK job market is terrible at moment. Bigger vaccine giant, for example, GSK has cut a lot people and focus on more in China and India. I tried a few companies and have not any luck so far. I have a British passport, which doesn’t help much at moment. So I have to reconsider to stay in academic. “Leo” mentioned the talent can always be successful whatever they are. I am not a talent and only a hard worker, so pretty much will struggle for years. Vaccine field may have its second gold period in next two decades. A prostate cancer vaccine has been authorised in US.
In molecular medicine, regardless of safety reason, China has authorised two licenses for adenovirus vector based gene targeting treatments since 2003, and everyone know China is only place to get stem cell based treatment. My colleagues and friends have mentioned about multidisciplinary research field, especially system biology, is the way to go forwards.
I am actually ready to move to US, but my family is not ready yet. I heard the competition is extremely explosive in US, especially with Chinese scientist. I would enjoy that if this is ture.
Again, I appreciate the nice suggestions from both of you.
It is a difficult question to answer. Here is some of my understanding and hopefully be useful for you. First I am not sure whether your interests are in academic or industry. Though some people may doing well in both fields, it usually take some time/luck and networking.
Vaccine is a relative mature industry, there are several big global vaccine companies available now, the market shares are stable. Gene therapy is still in early stage of development, most of the gene therapy or stem cell based company are still in the early stage of clinical development or pre-clinical stages. For vaccine, people put more focus on safer and more efficient methods. In technical area, more research activities will be on immuno-modulators and new delivery methods. In application area, therapeutic vaccine might have some big potential, such as in autoimmune disease, transplantation medicine, in certain cancer vaccines, etc.
Stem cell based medicine is an interesting area to get into. The basic science behind the stem cell is not solid, since it is basically interwoven with the understanding of system biology. But it does not means people will wait till the basic science is solid, the practical applications are already on the way, however, I tend to believe it will be ups and downs in near future.
You are young, and if you are passionate about biological sciences (dangerous path), I would suggest to choose a problem you deemed important, and go forward it. The future of biosciences is bright and probably rely heavily on integration of disciplines, include intra-life sciences sections and inter science (informatic, new chemical technology, detection methods, etc.). It is not fun to stay in the same narrow field for too long. The established fields need a new fresh look, and yourself also need to broaden your knowledge.
If you want to know how to get a high paid, stable, satisfactory job, sorry, I am still looking, too.
I am currently working as research assistant and completing my phD in vaccine development in UK. I am considering changing a field during my first posdoc. Basically, I want to stay in research but worry about the field of microbiology. We worked hard as the others, but impact factors of our publications are no great. My best first author paper is only in JBC. I have been offered two posdoc postions. One is from my phD supervisor and the project is on the effect a protein toxin on dendritic cells; another is to modify a rare adenovirus for gene therapy. I have also considered applying a position in stem cell research, too. However, I need to make a decision soon. I have been asking advices around. Some people said I am better stay since my academic record is good so far in infection field, some said molecular medicine (gene therapy) field is really hot and I should move. The thing is if I stay with my boss now, I will have 3 or 4 first author papers next three years. I would really appreciate you can give me some suggestions. I am 32 years old, and this should be the only time I can change a field.